The precise selection of the parameters in the Sintratec Kit gives the academics great freedom to research. Fabrizio explains: “By finely changing the printing parameters and/or the composition of the powder mixture, we can personalize the dissolution time of the printlets as we desire”. This can range from a few seconds to over 24 hours, or even days if implantable devices are printed.
To further reduce the dissolution time, Fabrizio developed printlets with lattice structures. Due to their large total surface area, printlets with a gyroid (type of lattice) structure dissolve much faster than those with a cylindrical shape. Such complex structures would be impossible to be manufactured using conventional production methods. Among the SLS printers, the Sintratec Kit is particularly suitable for laboratory applications due to its design: “An SLS printer with a strong laser might degrade the drug and a large printing platform would be an inconvenient for us in terms of material preparation and handling during the development phase”.